​​​​​​​Patient Outcomes Research To Advance Learning (PORTAL)

Patient Outcomes Research To Advance Learning (PORTAL) is a new research network that brings together leading health-care delivery systems to study the effectiveness of different approaches to diagnosis, treatment and management, in order to assist patients, their caregivers, and doctors in making better-informed decisions.

The PORTAL network consists of Kaiser Permanente, HealthPartners, and Denver Health, and their 10 affiliated research centers; these health care systems collectively enroll more than 12 million members. Stakeholder engagement is an integral component of PORTAL’S work, with patients, doctors, and other health system leaders actively engaged with researchers in every stage of study planning and design. We are building robust online communities to enable us to more broadly engage patients in this work.

The research network that PORTAL is building will help address critical questions, including comparing treatment and ongoing management options for:

  • Patients with a diagnosis of colorectal cancer
  • Adolescents and adults with severe congenital heart disease
  • Adults who are overweight or obese, including those who have pre-diabetes or diabetes

Through PORTAL, participating health care systems will expand their capacity to conduct studies for patients and doctors that provide better information about real world care delivery.


PORTAL is one of 29 networks in the National Patient-Centered Outcomes Research Network (PCORnet), which seeks to improve the nation’s capacity to conduct comparative effectiveness research by creating a large, representative network of care delivery systems and their data assets. PCORnet will enable the nation to harness for research the vast amounts of valuable health information created every day during routine patient visits. Funded by the Patient-Centered Outcomes Research Institute (PCORI), PCORnet will provide the answers that patients need, while directly involving them in decision-making about research priorities, patient privacy, and data security — thereby speeding the creation of new knowledge to guide treatment on a national scale.

Our Network

PORTAL is a network of three major U.S. health care systems, which collectively host 10 research centers and enroll more than 12 million members.

Learn more »